- Accreditation from the Society of Chest Pain Centers for Heart Failure
- Accredited with PCI (Percutaneous Coronary Intervention) for Cycle III
- Accredited with the American College of Radiology (ACR) in Radiation Therapy
- Southeast Missouri Hospital voluntarily employees The Joint Commission for its accreditation process.
- Recipient of American Heart Association's Get With Guidelines- Coronary Artery Disease Gold and Silver Performance Achievement Award
- Southeast Home Health and Southeast Hospice are accredited by The Joint Commission
- Accredited by the American Nurses Credentialing Center, a branch of the American Nurses Association, and redesigned as Magnet Hospital
- Accredited by the Society of Chest Pain Centers with PCI
- Certified by the Joint Commission as a Primary Stroke Center
- Southeast Missouri Hospital’s College of Nursing & Health Sciences, accredited by the Higher Learning Commission of the North Central Association of Colleges and Schools
- Accredited by the Missouri State Board of Nursing for the Southeast Missouri Hospital College of Nursing & Health Sciences
- Accredited by the Commission on Laboratory Accreditation of the College of American Pathologists
- Accredited by the American College of Surgeons’ Commission on Cancer
- Accredited by the Intersocietal Commission for the Accreditation of Vascular Laboratories
- Accredited by the American College of Surgeons’ Commission on Cancer for Radiation Therapy
- Accredited by the American College of Radiology
- Accredited by the American Association of Cardiovascular and Pulmonary Rehabilitation
- Licensure by the State of Missouri for Southeast Home Health
- Certification through the State of Missouri/Southeast Hospice
- Achieved the HealthGrades Outstanding Patient Experience Award™ and Patient Safety Excellence Award™ in 2009
- Designated as a Blue Cross/Blue Shield Distinction Center for Cardiac Care®
- Received the Gold Seal of Approval™ from The Joint Commission for Primary Stroke Centers
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